MesopotamiaMesopotamia. Mesopotamia is thought to be one of the places where early civilization developed. It is a historic region of West Asia within the Tigris-Euphrates river system. In fact, the word Mesopotamia means “between rivers” in Greek.

Which ancient river valley civilization was located along the Tigris and Euphrates rivers in the land of Mesopotamia?

Sumer civilization

One of the oldest known Mesopotamian cities, Nineveh (near Mosul in modern Iraq), may have been settled as early as 6,000 B.C. Sumer civilization arose in the lower Tigris-Euphrates valley around 5,000 B.C.