Comfortis® (spinosad) requires a prescription from your veterinarian, who is your best source of advice about your pet’s health care.

What is equivalent to Comfortis?

First of all, both Comfortis and Capstar are oral flea treatments. They both come in the form of a convenient, chewable tablet. Each of these medications work rapidly (Comfortis starts killing fleas within 30 minutes, and Capstar kills 90% of fleas within 4 hours).

How can I buy Comfortis?

With an active Comfortis prescription from a licensed veterinarian within the last 12 months, you can buy your pet Comfortis right here at or at your neighborhood Petco Pet Care Center.

What is comparable to Comfortis for dogs?

What is Capstar? Capstar is a tablet flea treatment for cats and dogs, given by mouth, to kill adult fleas.

Is Comfortis still available?

Comfortis can be found in your veterinarian’s office—your source for the best pet health care advice.

Is Trifexis and Comfortis the same?

Trifexis is a combination of two medications that handle fleas and parasites. Comfortis deals only with fleas. Trifexis can be given to puppies as early as 8 weeks and 5 pounds, while Comfortis is safe for puppies a minimum of 14 weeks old.

What is the main ingredient in Comfortis?


The active substance in Comfortis, spinosad, is an insecticide which works by interfering with certain receptors (nicotinic acetylcholine receptors) in the fleas’ nervous system, which results in their subsequent paralysis and death.

What is the best over the counter flea pill?

Frontline Plus is our top nonprescription recommendation because it kills ticks and fleas, controls flea infestations, and kills chewing lice, all with one easy application. When used primarily for flea control, each dose of Frontline Plus lasts up to three months.

Is Bravecto the same as Comfortis?

Comfortis uses Spinosad and begins to kill fleas within 30 minutes whereas Bravecto uses Fluralaner and begins to kill fleas in as little as 2 hours. If time to kill fleas is how you’re judging products, then Comfortis wins. Both Bravecto and Comfortis are safe for dogs when following directions.